PMED: The Next Generation of Extracellular Vesicle Manipulation

Unlock new possibilities in EV research with PMED (Portable Microstructured Electrochemical Fluidic Device) — a breakthrough tool designed for the ultrafast and controlled capture, loading, and release of extracellular vesicles.

How it works

PMED integrates advanced microfluidics and electrochemistry. It features a fluidic channel confined within 3D microstructured micro‑carbon fiber (µCF) electrodes, embedded in a flexible poly(dimethylsiloxane) (PDMS) matrix. These electrodes are stably coated with a target‑specific antibody (such as anti‑CD9 or anti‑CD63), enabling highly selective binding of EVs from complex biological samples.

Key advantages

• Speed: 40 minutes from the sample to the EV fraction, what dramatically reduces processing time compared to traditional methods (ultracentrifugation, precipitation)
• Precision: electrochemical control allows for gentle and efficient capture and on‑demand release of intact EVs.
• Specificity: antibody ensures isolation of subpopulations of interest.
• Simplicity: compact, portable design easily integrates into existing lab workflows.
• Versatility: the platform is adaptable — simply change the antibody coating to target different EV markers.

PMED is poised to transform diagnostics, therapeutics, and fundamental EV biology research.

Elevate your research. Embrace precision with PMED.