Our company is engaged in research and development of products for molecular biology, focusing on the mechanisms of regulation of cellular activity through RNA and DNA, including intercellular communication through exosomes. The products of our company allow you to immerse yourself in the very thick of the processes occurring in cells, to determine the principles of cell interaction during the development of a particular disease, to identify markers that signal the development of a disease. With the help of our company's products you can investigate pathogenesis if such diseases as oncology, neurodegenerative diseases, diabetes mellitus, microcirculation disorders, assess the immune status, including the body's response to viral influences and the identification of various types of immunity, identify hereditary and congenital genetic diseases. The main mission of our company is development of a personalized approach not to treat the disease but to predict and prevent the disease.
OUR
SERVICES
Design
We design mRNA with the desired expression profile (high-low, long-short, conditional) by exchanging UTRs and/or optimizing the codon usage in the coding sequence.
01
Produce
We use highly innovative, proprietary methods to synthesize high-quality, high-purity full-length mRNA.
02
Formulation
Any mRNA purchased from our company is possible to incorporate into any variant of nano-particles we work with.
03
KEY
TARGET
Exosomes
Exosomes are nano-sized, membrane-enclosed vesicles that released by nearly every cell type in the body. Exosomes contain various molecular constituents (genetic material and proteins) of their cell of origin, and act as powerful messengers between cells, ultimately providing a regulatory function for many cell processes.
01
mRNA
Matrix ribonucleic acid (mRNA, synonym - informational RNA, mRNA) - RNA containing information about the primary structure (amino acid sequence) of proteins. mRNA is synthesized on the basis of DNA during transcription, after which, in turn, is used during translation as a template for protein synthesis, whereby mRNA plays an important role in the “manifestation” (expression) of genes.
02
DNA
Deoxyribonucleic acid is a biopolymer, the monomers of which are nucleotides consisting of a carbohydrate, a nitrogenous base and phosphates. In the organism of living beings, DNA stores genetic information, its implementation and inheritance. DNA also encodes information about the structure of RNA and proteins. The main nucleotides encoding information are Adenine, Thymine, Cytosine and Guanine.
03
microRNA
MicroRNAs were first identified in Caenorhabditis elegans in 1993; However, their functional roles in human disease have not been evaluated for subsequent use for nearly a decade. MicroRNAs are evolutionarily conserved, small (average ≈18-24 nucleotides), single-stranded noncoding RNAs that regulate gene expression at the post-transcriptional level
04
OUR
KITS
Me-smrps
Specific mRNA primers set lot Me-smrps100-ххх
A set of specific primers for reverse transcription, allowing the production of specific cDNA.
A set of specific primers for reverse transcription, allowing the production of specific cDNA.
- Primers are presented for 500 genes, divided into separate specific sets by nosology, and by Numbers of individual primers.
1675 EUR
Me-sei50200
Specific Exosome isolation kit lot Me-sei50200-cd-xx
The Specific Exosome Isolation Kit allows the isolation of specific types of exosomes from a variety of biological materials.
The Specific Exosome Isolation Kit allows the isolation of specific types of exosomes from a variety of biological materials.
- The principle of the kit is based on precipitation with further specific isolation using specific antibodies.
583 EUR
Me-rt50
Reverse Transcription for PCR-RT kit lot Me-rt50
Specific reverse transcription kit contidioned for specific primers.
Specific reverse transcription kit contidioned for specific primers.
315 EUR
Me-pri50200
Plasma RNA isolation kit lot Me-pri50200
The kit for the isolation of extracellular circulating RNA from plasma, allowing efficiently isolation RNA preserving its structure from plasma.
The kit for the isolation of extracellular circulating RNA from plasma, allowing efficiently isolation RNA preserving its structure from plasma.
- The principle of the kit is based on the precipitation of RNA on a special membrane located on the columns, washing and further elution of RNA
415 EUR
Me-pei20
Plasma Exosome isolation kit lot Me-pei20ХХХX
The kit for the isolation of exosomes from blood plasma allows efficient isolation of exosomes from blood plasma.
The principle of the kit is based on gradient separation of fractions, filtration, centrifugation and subsequent precipitation, which allows exosomes isolation.
The kit for the isolation of exosomes from blood plasma allows efficient isolation of exosomes from blood plasma.
The principle of the kit is based on gradient separation of fractions, filtration, centrifugation and subsequent precipitation, which allows exosomes isolation.
- Various options are available depending on the volume
320 - 650 EUR
Me-eta01100
Exosome Targeted antibodies lot Me-eta01100-cd-xx
Selected highly purified antibodies for planning experiments with exosomes.
Available options of antibodies to CD markers (100ul)
Selected highly purified antibodies for planning experiments with exosomes.
Available options of antibodies to CD markers (100ul)
340 EUR
Me-ecc1212
Exosome quality control kit lot Me-ecc1212
- Exosome quality control kit based on the calculation of ratio of fluorescence intensity of exosome mambrane and endogenous markers to fluorescence intensity of not specific for exosomes markers.
540 EUR
Me-eri50250
Exosomal mRNA isolation kit lot Me-eri50250
The kit for the isolation of mRNAs from exosomes allowing to efficiently isolate mRNAs from exosomes.
The kit for the isolation of mRNAs from exosomes allowing to efficiently isolate mRNAs from exosomes.
- The principle of the kit is based on the exosomes sedation following its degradation and mRNA precipitation on a special membrane located on columns, washing and further elution of mRNA
457 EUR
Me-pri50200a
Exosomal DNA isolation kit lot Me-pri50200
The kit for the isolation of extracellular circulating DNA from plasma, allowing efficiently isolating DNA from plasma.
The principle of the kit is based on the precipitation of DNA on a special membrane located on the columns, washing and further elution of DNA
The kit for the isolation of extracellular circulating DNA from plasma, allowing efficiently isolating DNA from plasma.
The principle of the kit is based on the precipitation of DNA on a special membrane located on the columns, washing and further elution of DNA
438 EUR
Me-ctcc1005
CTC culture kit lot Me-ctcc1005
The circulating tumor cell culture kit allows for the maintenance of the culture of circulating tumor cells.
The circulating tumor cell culture kit allows for the maintenance of the culture of circulating tumor cells.
- The principle of the kit is based on the use of specific growth factors giving an advantage in the proliferation of circulating tumor cells, thereby enriching the culture with the target cells.
1100 EUR
Me-ctci1010
Circulating tumor cells isolation kit lot Me-ctci1010
The kit for the isolation of circulating tumor cells allowing to isolate 5 to 50 circulating tumor cells from 10 ml of whole blood.
The kit for the isolation of circulating tumor cells allowing to isolate 5 to 50 circulating tumor cells from 10 ml of whole blood.
- The principle of the kit is based on gradient separation of fractions with further washing of the fraction enriched with circulating tumor cells, and determination of the number of isolated cells using specific antibodies.
745 EUR
Me-cei25100
Cancer exosome isolation kit lot Me-cei25100-m-xx
The kit for the isolation of tumor exosomes allows the isolation of exosomes secreted by tumor cells from various biological materials.
The principle of the kit is based on precipitation with further differential isolation with specific antibodies.
The kit for the isolation of tumor exosomes allows the isolation of exosomes secreted by tumor cells from various biological materials.
The principle of the kit is based on precipitation with further differential isolation with specific antibodies.
640 EUR
Me-emri50250
The kit for the isolation of miRNAs from exosomes allowing to efficiently isolate miRNAs from exosomes.
- The principle of operation of the kit is based on the exosomes sedation following its degradation and miRNA precipitation on a special membrane located on columns, washing and further elution of microRNA
390 EUR
Me-edcl-200
Lyophilizates of enriched for exosomes supernatant from different cell lines. Exosomes enriched biomaterial may be used for working out storage and isolation conditions.
1237 EUR
Me-dcps100
A set of target primers allowing to enrich specific DNA regions. There are primers for 500 genes available for purchase. Primers are divided into sets based on a specific pathologic state or a disease. For purchase there are available both options: primers sets and specific primers and customized primers sets.
980 EUR
Ref-cr
Reference DNA set for mutations in colorectal cancer. cr-1.0
This is a kit containing DNA sequences with 100 most relevant mutations for colorectal cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
2780 EUR
Ref-br
Reference DNA set for mutations in breast cancer. br-1.0
This is a kit containing DNA sequences with 100 most relevant mutations for breast cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
This is a kit containing DNA sequences with 100 most relevant mutations for breast cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
2780 EUR
Ref-lc
Reference DNA set for mutations in lung cancer. lc-1.0
This is a kit containing DNA sequences with 100 most relevant mutations for lung cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
This is a kit containing DNA sequences with 100 most relevant mutations for lung cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
2780 EUR
Ref-prc
Reference DNA set for mutations in prostate cancer. prc - 1.0
This is a kit containing DNA sequences with 100 most relevant mutations for prostate cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
This is a kit containing DNA sequences with 100 most relevant mutations for prostate cancer. It can be used as an internal control in the process of the designing different kits for mutation detection or improvement of the detection of different mutations.
2780 EUR
MR-PAT
PI3K/AKT/mTOR This kit includes PCR mix, polymerase enzyme and primers for main miRNAs, involved in regulation of PI3K/AKT/mTOR signalling pathway.
Request a quote
MR-MP
MAPK pathway. This kit includes PCR mix, polymerase enzyme and primers for main miRNAs, involved in regulation of MAPK signalling pathway.
Request a quote
MR-Ki67
Ki67 proliferation pathway. This kit includes PCR mix, polymerase enzyme and primers for main miRNAs, involved in regulation of proliferation signalling pathway.
Request a quote
MR-CA
Cell apoptosis. This kit includes PCR mix, polymerase enzyme and primers for main miRNAs, involved in regulation of main regulators of cell apoptosis signalling pathway.
Request a quote
MR-CCSE
Cell cycle switches pathway. This kit includes PCR mix, polymerase enzyme and primers for main miRNAs, involved in regulation of expression of cell cycle switches signalling pathway.
Request a quote
FAQ
The main mission of our company is development of a personalized approach not to treat the disease but to predict and prevent the disease
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